Our main mission is to commemorate the plight of victims of the Transatlantic Slave Trade and to exemplify the miracle of human resilience, promote reconciliation and peace among mankind, and inspire worldwide efforts to enhance and protect freedom and human dignity. As a corollary, we will also retell the stories of the struggles for emancipation by countries in Africa which were under colonial rule.The unique power and authenticity of the message of this cultural heritage destination will capture key points and educate millions of people globally of the history of the Transatlantic Slave Trade and work diligently to accomplish the following goals and objectives:

• Bring closure to millions of the descendants of both victims and perpetrators to stand together in the prevention of another human tragedy of this kind from recurring.
• Through remembering the human resiliency and survival of the millions of Africans who were captured and enslaved, we will celebrate the remarkable victories and global achievements of generations of the African Diaspora, including the people of West Africa.
• Promote a positive image and change of attitude towards the ancestral and cultural values of people of African descent by elucidating the beauty, grandeur and sophistication of the ancient Ghanaian and Songhai Empires.
• Illustrate the detrimental impact of the massive loss of human capital by West Africa in particular and the African continent as a whole as a result of the Transatlantic Slave Trade.
• Appeal to the innate potential of any African on the continent and those in the Diaspora to eschew parochialism and stand guard to fight any system orchestrated to perpetually keep them down in the comity of humanity.
• Inspire visitors to the Museum and leaders worldwide to confront racism, discrimination, human trafficking, religious intolerance, greed, hatred, apathy, and the promotion of human dignity.
• Remember and honor the abolitionists and freedom fighters of all races and cultures throughout the world.
• Work to reverse the lingering negative psychological impact caused by centuries of widespread defamation of African culture and character.
• Improve the esteem of Continental Africa and the Diaspora by counteracting the negative imagery established as a result of the institutions of the African Slave trade, racial discrimination, and African colonialism.
• GNMoSaF will work closely with many key segments of the global community to make a positive impact on our world.
• As a living memorial to the Transatlantic Slave Trade, we will work assiduously to help stop and prevent human trafficking in the future through our programs.

There has been worldwide support for the project including the Government of the Peoples’ Republic of China which has pledged to donate resources. The National Museum of African American History and Culture of the Smithsonian Institution in the U.S. will be the sister museum of the Ghana National Museum of Slavery and Freedom and will be consulted, along with other world-renowned museums for content, artifact collection and sharing, and operation of the museum.